Serums are able to go deeper into the skin's layers unlike creams and lotions says Heather Bennett, esthetician at Beverly Hills Rejuvenation Center. "Anti-wrinkle serums are more liquid than solid and is a better product to use for skin penetration as it gets to multiple layers of the skin more quickly and easily. The major benefits of serums are that they offer the most lightweight formula and give the most intensive results" adds Bennett. "To help reduce environmental toxins, build collagen and elastin and smooth fine lines and wrinkles Anti-aging serums are a must" adds Dr. Klein. But aside from reversing the changes caused by aging, serums can also help prevent premature wrinkles and fine lines from developing, says Dr. Sivak. "There are many ingredients that can prevent oxidation and modification of cellular components, including the very important DNA mutations caused by UV radiation," Dr. Sivak explains. "Other ingredients can prevent lipid oxidation, preserving cellular integrity."